Escola Paulista de Medicina
Postgraduate Program in Urology

Research Projects

Cellular and molecular analyses of semen from patients with testicular cancer.

Date: 01/01/2010

To study the mechanisms of cellular and molecular alterations in semen samples from men with testicular cancer, in order to identify better methods of fertility preservation.

Faculty Researchers

Renato Fraietta and Ricardo Pimenta Bertolla

Student body

Rosana Xavier Souza

Machine-learning application to study the mechanism of evolutive urological tumors

Date: 01/11/2018

This project aims to screen in silico and experimental data to follow and determine molecular markers, as well as their association with clinical data, in the study of urological tumors.

Faculty Researchers

Hatylas Felype Zaneti de Azevedo, Mariana Antoniassi and Paula Intasqui Lopes

Student Body

Tiago Aparecido Silva and Jorge Luis Wilson Junior 

Application of metabolomics in the global evaluation of steroids biosynthesis.

Date: 01/02/2012

Steroidomic processes associated with male fertility are still poorly understood. Because the testis is an organ with an intense steroidogenic activity, it is essential to understand the role of this activity on male fertility.

Funding: Chamada Fleury de Pesquisa

Faculty Researchers

Ricardo Pimenta Bertolla, Paula Intasqui Lopes and João Diego Agostini Losano

Student Body

Renata Cristina de Carvalho

Associated Researchers from Grupo Fleury

Karina Helena Morais Cardozo and Valdemir Melechco Carvalho

 

Aplication of post-genomic technology to study in vitro culture of embryo and embryonic stem-cells .

Date: 01/04/2015

To use post-genomic technology for the study and determination of in vitro culture conditions for oocytes and embryos, as well as stem cells.

Funding: FAPESP and CAPES

Faculty Researcher

Edson Guimarães Lo Turco and Mariana Camargo

Student Body

Gabrielle Ferrante Alves de Moraes, Karla Pacheco de Melo and Lilian Barreto

Prognostic aspects and surgical complications in renal transplant.

Date: 09/27/2016

Survey of database on transplant patients to assess the prognostic effects and complications of kidney transplant surgery.

Faculty Researcher

Wilson Ferreira Aguiar

Student Body

Mauro Miguel de Lima Sousa Barbosa, Guilherme Alonso Daud Patavino, Matheus Brandão Vasco, Rafael Haddad Astolfi and Veridiana Costa Andrioli.

Evaluation of voiding dysfunction and its impact on life quality.

Date: 01/01/2008

To deepen the knowledge regarding the pathophysiological mechanisms and to develop advanced and innovative methods for the treatment of vesico-sphincteric dysfunctions.

Faculty Researcher

Fernando Gonçalves de Almeida 

Student Body

Mariana Rhein Felippe, Marcia Eli Girotti de Azevedo, Carla Lemos and Monique Rodrigues

Systems biology and sperm functional quality in the study of male infertility.

Date: 01/10/2012

The aim of this approach is to determine the protein profile of seminal plasma and sperm samples from healthy men and to compare it to samples from men under different clinical conditions. In this study, we also aim to analyse the association between the

Funding: CNPq and FAPESP

Faculty Researchers

Ricardo Pimenta Bertolla, Mariana Camargo, Mariana Pereira Antoniassi and Paula Intasqui Lopes

Student Body

Luana Nayara Galego Adami

Biomarkers of testicular function in semen and sperm of adolescents with varicocele.

Date: 03/01/2015

To study the protein and molecular markers of male infertility and of testicular function in adolescents with varicocele.

Funding: CNPq

Faculty Researcher

Agnaldo Pereira Cedenho and Ricardo Pimenta Bertolla 

Student body

Mika Alexia

Development of surgical techniques and application of tissue engeneering in terapeutic of pediatric urological affections.

Date: 03/01/2018

The aim of this project is to develop and substantiate specific surgical techniques for the approach of pediatric patients, as well as to develop and use technologies based on tissue engineering for making tissues to be used in grafts to correct urological changes in children and adolescents. 

Faculty Researcher

Agnaldo Pereira Cedenho

Student Body

Samuel Saiovici and Veridiana Costa Andrioli

Development of an urinary bladder-derived acellular.

Date: 03/01/2010

Development of a matrix for translational development.

Funding:FAPESP

Faculty Researcher

Fernando Gonçalves de Almeida

Associated Researchers

Milton Skaff Junior and João Paulo Zambon

Analysis of the lipidomic and metabolomic profile of follicular fluid, cumulus cells, and blood plasma of women with different causes of infertility undergoing in vitro fertilization treatment.

Date: 08/01/2012

Lipidomic and metabolomic analysis in follicular fluid, cumulus cells, blood plasma and culture medium of embryos of infertile women submitted to in vitro fertilization.

Funding: FAPESP

Faculty Researcher

Edson Guimarães Lo Turco

Student Body

Gabrielle Ferrante Alves de Moraes

Effect of supplements addition in human semen processing and cryopreservation.

Date: 02/11/2016

Analysis of sperm quality submitted to seminal processing and semen cryopreservation after supplementation with vitamin E, L-carnitine, glucose and / or oxidative phosphorylation blocker. 

Faculty Researcher

Ricardo Pimenta Bertolla

Student body

Luana Nayara Gallego Adami

Effect of sperm DNA fragmentation on the lipid profile of mouse blastocyst.

Date: 02/04/2012

To elucidate the male effects on the initial embryo development.

Funding: FAPESP

Faculty Researchers

Edson Guimarães Lo Turco and Paula Intasqui

Student Body

Lilian Barreto and Mika Alexia

Comparative study between pulverization or fragmentation and stone removal during flexible urolitotripsia.

Date: 09/27/2016

Comparative study between pulverization or fragmentation and stone removal during flexible urolitotripsia. 

Faculty Researchers

Mariana Camargo and Marcus Vinicius Sadi

Student Body

Alex Elton Meller and Gustavo Freschi

Study of erectile dysfunction in patients submitted to renal transplant.

Date: 09/27/2016

Faculty Researcher

Wilson Ferreira Aguiar

Student Body

Matheus Brandão Vasco

Study of semen toxicity in spinal cord injured men.

Date: 04/01/2017

Patients with spinal cord injury have anejaculation and seminal plasma toxicity. This project aims to study the cellular and molecular mechanisms of these changes, as well as the effect of treatment with oral anti-inflammatories - which have been shown to improve seminal quality. 

Funding: FAPESP

Faculty Researchers

Ricardo Pimenta Bertolla, Mariana Camargo and Paula Intasqui Lopes

Student body

Karla Pacheco and Lilian Barreto

Associated Researches from University of Miami (USA)

Nancy Brackett and Charles Lynne

Study of a new approach for an early detection of varicocele-induced testicular dysfunction.

Date: 04/02/2012

To characterize, from the cellular and molecular point of view, the mechanisms that determine the testicular alteration in adolescents and adults with varicocele.

Funding: Chamada Fleury de Pesquisa

Faculty Researchers

Ricardo Pimenta Bertolla

 Student Body

Aram Minas, Valter Luiz Maciel and Gustavo Nogueira

Associated Researchers from Grupo Fleury

Karina Helena Morais Cardozo and Valdemir Melechco Carvalho

Study of seminal mollecular environment and its relation with sperm fuctional quality.

Date: 07/01/2014

Study of sperm function biomarkers in various cases of male infertility.

Funding:FAPESP and CAPES

Faculty Researchers

Paula Intasqui Lopes, Ricardo Pimenta Bertolla and Mariana Camargo

Student Body

Beatriz Braga Ribeiro and Leticia Kaory Tamashiro

Impact of obesity on sperm functional quality and semen proteomic mechanisms.

Date: 09/01/2010

This study aims to verify how obesity may alter spermatogenesis and semen protein expression.

Funding: FAPESP

Faculty Researchers

Ricardo Pimenta Bertolla and Renato Fraietta

Student body

Renata Cristina de Carvalho

Technical innovations and prognostic factors in renal cancer surgery.

Date: 10/01/2013

To evaluate the real role of innovations in patient survival and its correlation with the molecular and histological tumor type, as well as with possible tumor markers in kidney tumors.

Faculty Researchers

Hatylas Felipe Zaneti de Azevedo, Marcus Vinicius Sadi and Stenio de Cássio Zequi

Student Body

Jorge Luis Wilson Junior, Renato Meirelles Mariano da Costa Junior and Tiago Aparecido Silva

Associated Researchers

Thomé Decio Pinheiro Barros Junior and Carlos Eugenio Lira Tenório.

 

Association between heat shock proteins (HSP) expression and oxidative stress in patients with varicocele.

Date: 07/01/2015

Evaluation of seminal levels of heat shock proteins and their association with seminal oxidative stress in men with varicocele.

Faculty Researchers

Ricardo Pimenta Bertolla and Mariana Pereira Antoniassi

Student Body

Gustavo Augusto Keusch Albano Nogueira

Seminal subjacent pathways to male infertility clinics.

Date: 10/01/2017

The aim of this project is to study the molecular pathways that can be observed in different causes of male infertility. 

Faculty Researchers

Renato Fraietta, Ricardo Pimenta Bertolla and Mariana Pereira Antoniassi

Faculty Researchers

Renata Cristina de Carvalho and Matheus Ferreira Groner

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